Cantor
Cantor is a front-end to powerful mathematics and statistics packages.
8 Alternatives To Cantor
Beaker
Open Source Polyglot Data Science Tool
Calculist
The open-source, web-based thinking tool that facilitates effective thinking for solving problems.
Carbide
A new kind of programming environment
Eve
Programming designed for humans
Kajero
Interactive JavaScript notebooks - create good-looking, responsive, interactive documents.
Observable HQ
Interactive code examples/posts
iPython
iPython provides a rich toolkit to help you make the most out of using Python interactively.