PICO-8
Lua-based fantasy console for making and playing tiny, computer games and programs.
17 Alternatives To PICO-8
8bitdash
Animated 8-bit browser home screens

AppGameKit
AppGameKit is a game development platform for mobile devices.

Aseprite
Aseprite is an art program dedicated to the creation of pixel art.
Bitsy
Bitsy is a small, fast, embeddable, durable in-memory graph database that implements the Blueprints API.

Corona SDK
Cross-platform mobile app development.
CryPixels
Procedural Sprite Generator
LIKO-12
Fantasy console built with the Love 2D game engine.
Moai
Moai is a spiritual successor to one of the elder gods of pixel editing: Autodesk Animator.
PX8
Open-source, Rust based fantasy console.
PulseBoy
Web-based musical sequencer which only uses 8bit sounds
Pyxel
Retro game engine for Python inspired by fantasy consoles.

Riko4
Lua-based A fantasy computer / game engine
SpritePad
The easiest way to create your CSS sprites

TIC-80
TIC-80 is a fantasy computer where you can make, play and share tiny games.
Voxatron
Voxel-based fantasy console

Zany80
The fantasy console built around the Z80
nano JAMMER
Full-featured fantasy console that runs entirely in the browser and supports Google Drive