PySide

Qt for Python - Qt Wiki

20 Alternatives To PySide

Agar

Agar GUI
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Appcelerator Titanium

Appcelerator Open Source

Avalonia

A multi-platform .NET UI framework
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Blender

Blender is the open source, cross platform suite of tools for 3D creation.

Electron

Build cross platform desktop apps with web technologies

FLTK

Fast Light Toolkit - Fast Light Toolkit (FLTK)
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Fox toolkit

fox-toolkit.org
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GTK

GTK+ is a multi-platform toolkit for creating graphical user interfaces.

JUCE

JUCE is a wide-ranging C++ class library for building rich cross-platform applications and plugins…
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JavaFX

JavaFX is the next step in the evolution of Java as a rich client platform.

Nana C Library

Nana C++ Library - a modern C++ GUI library

PhoneGap

Easily create apps using the web technologies you know and love: HTML, CSS, and JavaScript.

PySimpleGUI

A simple to use GUI that can create custom GUIs

Qt

C++
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Qt Creator

Qt Creator is a cross-platform C++, JavaScript and QML integrated development environment. It is the fastest, easiest and most fun experience a C++ developer could wish for.
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React Native

A framework for building native apps with React

Ultimate++

Ultimate++ is a C++ cross-platform rapid application development framework
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Unity

The multiplatform game creation tools for everyone.
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wxSVG

wxSVG is C++ library to create, manipulate and render SVG files.

wxWidgets

wxWidgets: Cross-Platform GUI Library