TurboGears
TurboGears is a web framework to create a database-driven, ready-to-extend application in minutes.
22 Alternatives To TurboGears
CherryPy
CherryPy allows developers to build web applications in much the same way they would build any other object-oriented Python program.
FastAPI
FastAPI is an Open Source, modern, fast (high-performance), web framework for building APIs with Python 3.6+ based on standard Python type hints.
Pyramid
Pyramid is an open source web framework written in Python and is based on WSGI.
Tornado
A Python web framework and asynchronous networking library, originally developed at FriendFeed